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- Recombinant Human PP2C alpha/PPM1A,BR
Recombinant Human PP2C alpha/PPM1A,BR
Recombinant Human PP2C alpha/PPM1A
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产品属性 Product Attributes
基本信息
别名: Protein Phosphatase 1A;Protein Phosphatase 2C Isoform Alpha;PP2C-Alpha;Protein Phosphatase IA;PPM1A;PPPM1A中文名称: Recombinant Human PP2C alpha/PPM1A
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状): Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
产品信息
背景说明: Protein Phosphatase 1A (PPM1A) is a member of the PP2C family of Ser/Thr protein phosphatases which are known to be negative regulators of cell stress response pathways.PPM1A has a broad specificity.PPM1A negatively regulates the activities of MAP kinases and MAP kinase kinases.Also,it negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3,resulting in their dissociation from SMAD4,nuclear export of the SMADs and termination of the TGF-beta-mediated signaling.In addition,PPM1A can dephosphorylate cyclin-dependent kinases,and thus may be involved in cell cycle control.来源: E.coli
其它标识
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.产品介绍 Product Introduction
暂无数据注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。