Recombinant Human CD14,BR

产品属性 Product Attributes

基本信息

别名： Monocyte Differentiation Antigen CD14;Myeloid Cell-Specific Leucine-Rich Glycoprotein;CD14
中文名称: Recombinant Human CD14
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： CD14 is a cell surface glycoprotein that is preferentially expressed on monocytes/macrophages.CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a pattern recognition receptor that binds lipopolysaccharides (LPS) and a variety of ligands derived from different microbial sources.The binding of CD14 with LPS is catalyzed by LPS binding protein (LBP).Toll like receptors have also been implicated in the transduction of CD14-LPS signals.Soluble CD14 can be released from the cell surface by phosphatidyinositolspecific phospholipase C and has been detected in serum and body fluids.High concentrations of soluble CD14 have been shown to inhibit LPS mediated responses.However，soluble CD14 can also potentiate LPS response in cells that do not express cell surface CD14.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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