Recombinant Human CD300b/CD300LB/LMIR5,BR

产品属性 Product Attributes

基本信息

别名： CD300b;CLM-7;CLM-7;CMRF35-A2;IREM-3;IREM3;TREM-5;TREM5;CD300LB
中文名称: Recombinant Human CD300b/CD300LB/LMIR5
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： CD300LB，also known as CD300b，LMIR5，CLM-7，and IREM-3，is a glycoprotein member of the immunoglobulin superfamily.LMIR5 is expressed on the surface of myeloid lineage cells.It forms noncovalent cis-homodimers and cis-heterodimers with other CD300 family proteins，and the composition of these dimers affects the cellular response.Antibody cross-linking of LMIR5 induces mast cell granule release and cytokine production as well as its tyrosine phosphorylation of LMIR5 (in human).LMIR5 interacts with TIM1 and TIM4 which regulate T cell activation and are themselves binding partners.TIM1 interactions with LMIR5 mediate mast cell activation and the accumulation of neutrophils at sites of TIM1 up-regulation on damaged renal tubule epithelial cells.Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP，and also independently by recruitment of GRB2.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

暂无数据

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。