Recombinant Mouse SLAMF3/T-lymphocyte Surface Antigen Ly-9/CD229,BR

产品属性 Product Attributes

基本信息

别名： T-lymphocyte surface antigen Ly-9;Cell surface molecule Ly-9;Lymphocyte antigen 9;SLAM family member 3;SLAMF3;Signaling lymphocytic activation molecule 3;CD229;Ly9;Ly-9
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： CD229(SLAMF3) is a type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family.Mature mouse CD229 consists of a 406 aa extracellular domain (ECD) with two Ig-like V-set and two Ig-like truncated C2-set domains，a 21 aa transmembrane segment，and a 180 aa cytoplasmic domain with two immunoreceptor tyrosinebased switch motifs ITSMs.Within the first two Ig-like domains that are common to all SLAM proteins，mouse CD229 shares 22%-36% aa sequence identity with mouse 2B4，BLAME，CD2F10，CD84，CRACC，NTBA，and SLAM.CD229 is expressed on T，B，and NK cells，thymocytes and monocytes.Homophilic binding between CD229 molecules is mediated by the N-terminal Ig-like domain.Human and mouse CD229 exhibit crossspecies binding.Antigen stimulation of lymphocytes induces CD229 clustering to sites of T cell-B cell contact.Antibody ligation of CD229 can inhibit T cell activation，but CD229 knockout mice show impaired T cell immune responses，suggesting a potential role for CD229 in T cell activation or costimulation.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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