Recombinant Human T-cell Immunoglobulin and Mucin Domain-containing Protein 4/Tim-4,BR

产品属性 Product Attributes

基本信息

别名： T-cell immunoglobulin and mucin domain-containing protein 4;TIMD-4;T-cell immunoglobulin mucin receptor 4;TIM-4;T-cell membrane protein 4;TIMD4;TIM4
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： T-cell Immunoglobulin and Mucin Domain-containing Protein 4(TIM-4) belongs to the immunoglobulin superfamily，is a member of the TIM family of immune regulating proteins.TIMs are type I transmembrane proteins with one Ig-like V domain and one Ser/Thr-rich mucin domain.Structurally，TIM-4 is distinguished from other TIMs by the presence of an RGD motif in its Ig domain and the lack of a site for tyrosine phosphorylation in its cytoplasmic tail.The mucin domain in TIM-4 is larger than in TIM-1 or TIM-3.TIM-4 is expressed by macrophages and mature dendritic cells but not by lymphocytes.it is Involved in regulating T-cell proliferation and lymphotoxin signaling.The interaction of TIM-4 with TIM-1 induces costimulatory and hyperproliferative signals in T cells.TIM-4 binds specifically to TIM-1 which is also the cellular receptor for the hepatitis A virus，and has been implicated in the development of asthma.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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