Recombinant Human Galectin-8,BR

产品属性 Product Attributes

基本信息

别名： Galectin-8;Gal-8;Po66 Carbohydrate-Binding Protein;Po66-CBP;Prostate Carcinoma Tumor Antigen 1;PCTA-1;LGALS8
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥80% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： The Galectin family of proteins，with specificity for Nacetyllactosaminecontaining glycoproteins，consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs).They also possess hemagglutination activity，which is attributable to their bivalent carbohydrate binding properties.Galectins are active both intracellularly and extracellularly.Although they are localized primarily in the cytoplasm and lack a classical signal peptide，galectins can also be secreted by one or more unidentified，non-classical，secretory pathways.They have diverse effects on many cellular functions including adhesion，migration，polarity，chemotaxis，proliferation，apoptosis，and differentiation.Galectins may therefore play a key role in many pathological states，including autoimmune diseases，allergic reactions，inflammation，tumor cell metastasis，atherosclerosis，and diabetic complications.The galectins have been classified into the prototype galectins(1，2，5，7，10，11，13，14)，which contain one CRD and exist either as a monomer or a noncovalent homodimer.The chimera galectins(Galectin3) containing one CRD linked to a nonlectin domain，and the tandemrepeat Galectins(4，6，8，9，12) consisting of two CRDs joined by a linker peptide.Galectins lack a classical signal peptide and can be localized to the cytosolic compartments where they have intracellular functions.However，via one or more as yet unidentified nonclassical secretory pathways，galectins can also be secreted to function extracellularly.Individual members of the galectin family have different tissue distribution profiles and exhibit subtle differences in their carbohydrate-binding specificities.Each family member may preferentially bind to a unique subset of cell surface glycoproteins.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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