Recombinant Mouse Natural Cytotoxicity Triggering Receptor 1/NCR1/NKP46,BR

产品属性 Product Attributes

基本信息

别名： Activating receptor1;mAR-1;Lymphocyte antigen94;Naturalkiller cell p46-related protein;NK-p46;NKp46;mNKp46
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Natural cytotoxicity triggering receptor 1(NKp46/NCR1) is a single-pass type I membrane protein.It consists of two extracellular Ig-like domains followed by a short stalk region，a transmembrane domain containing a positively charged amino acid residue，and a short cytoplasmictail.NKp46 is predominantly expressed in the embryo.It has a positive charge in its transmembrane domain that permits association with the ITAM-bearing signal adapter proteins，CD3 zeta and Fc epsilon RI gamma.These receptors are expressed almost exclusively by NK cells and play a major role in triggering some of the key lytic activities of NK cells.Studies with neutralizing antibodies indicate that the three NCR are primarily responsible for triggering the NK-mediated lysis of many human tumor celllines.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/μg(1 EU/μg)as determined by LAL test.

产品介绍 Product Introduction

暂无数据

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。