Recombinant Human Dual specificity protein phosphatase 3/DUSP3,BR

产品属性 Product Attributes

基本信息

别名： Dual specificity protein phosphatase 3;DUSP3;Dual specificity protein phosphatase VHR;Vaccinia H1-related phosphatase;VHR
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥90% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Human DUSP3 belongs to the dual specificity protein phosphatase subfamily.DUSPs are a heterogeneous group of protein phosphatases that can dephosphorylate both phosphotyrosine and phosphoserine/phosphothreonine residues within the one substrate.These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues.DUSPs are major modulators of critical signalling pathways that are dysregulated in various diseases.They negatively regulate members of the mitogen-activated protein kinase superfamily，which are associated with cellular proliferation and differentiation.DUSP3 is expressed in human tissues including breast and ovarian.DUSP3 shows activity both for tyrosine-protein phosphate and serine-protein phosphate，but displays a strong preference toward phosphotyrosines.Human DUSP3 specifically dephosphorylates and inactivates ERK1 and ERK2.
来源： E.coli

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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