Recombinant Human Guanidinoacetate N-methyltransferase/GAMT,BR

产品属性 Product Attributes

基本信息

别名： Guanidinoacetate N-methyltransferase;GAMT;PIG2;TP53I2
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,1mMDTT,pH 8.0 .
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： GAMT is a methyltransferase which belongs to the class I-like SAM-binding methyltransferase superfamily.It contains one RMT2 (arginine N-methyltransferase 2-like) domain and is expressed in liver.GAMT converts guanidoacetate to creatine，using S-adenosylmethionine as the methyl donor.Defects in GAMT are the cause of guanidinoacetate methyltransferase deficiency，which is an autosomal recessive disorder characterized by developmental delay/regression，mental retardation，severe disturbance of expressive and cognitive speech，intractable seizures and movement disturbances，severe depletion of creatine/phosphocreatine in the brain，and accumulation of guanidinoacetic acid in brain and body fluids.
来源： E.coli

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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