Recombinant Human F9/Coagulation factor Ix chain,BR

产品属性 Product Attributes

基本信息

别名： F9;Coagulation factor IX;Christmas factor;Plasma thromboplastin component;Coagulation factor IXa light chain;Coagulation factor IXa heavy chain
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,10% Glycerol,pH8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Coagulation factor IX（F9)，is a member of the peptidase S1 family.It contains two EGF-like domains，a Gla domain and a peptidase S1 domain.It is primarily expressed in the liver and secreted in plasma.Factor IX is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ ions，phospholipids，and factor VIIIa.Mutations in position 43 and 46 prevents cleavage of the propeptide，mutation in position 93 probably fails to bind to cell membranes，mutation in position 191 or in position 226 prevent cleavage of the activation peptide.Mutations of human F9 can result in thrombophilia and recessive X-linked hemophilia B (HEMB).An X-linked blood coagulation disorder characterized by a permanent tendency to hemorrhage，due to factor IX deficiency.It is phenotypically similar to hemophilia A，but patients present with fewer symptoms.Many patients are asymptomatic until the hemostatic system is stressed by surgery or trauma.
来源： Human Cells

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。