Recombinant Mouse SLAMF5/SLAM Family Member 5/CD84,BR

产品属性 Product Attributes

基本信息

别名： SLAM family member 5;Cd84;Leukocyte differentiation antigen CD84;Signaling lymphocytic activation molecule 5;CD84;Ly-9B;SLAMF5;CD84 antigen;CD84 molecule;SLAM family member 5
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： CD84，also called SLAMF5，is a member of the CD2 subgroup of the immunoglobulin receptor superfamily.Members of this CD2 subgroup mediate signal transduction through the interaction of its immunoreceptor tyrosine-based switch motifs (ITSM) in the intracellular region and the SH2 domain of adaptor molecules SAP (SLAM-associated protein) and EAT-2 (EWS-activated transcript 2)，and accordingly modulate both adaptive and innate immune responses.CD84 expression has been documented on several hematopoietic cell types，including monocytes，macrophages，dendritic cells，B lymphocytes，and platelets.Activation of cell surface CD84 initiates a signaling cascade involving its intra-cytoplasmic tyrosine residues that results in Bcl-2 upregulation，which in turn enhances cell survival.Either immunoneutralization or blockade of CD84 with a CD84 extracellular domain protein fragment induces cell death in vitro and in vivo.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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