Recombinant Human KIR2DL3/NKAT2/CD158b2,BR

产品属性 Product Attributes

基本信息

别名： Killer cell immunoglobulin-like receptor 2DL3;KIR2DL3;CD158b2;NKAT2;CD158 antigen-like family member B2;KIR-023GB;Killer inhibitory receptor cl 2-3;MHC class I NK cell receptor;NKAT-2;p58 NK receptor CL-6
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Killer-Cell Immunoglobulin-Like Receptors (KIRs) are important cells of the immune system.KIRs are a family of Natural Killer (NK) Cells surface glycoproteins.KIRs control the killing function of these cells by interacting with MHC class I molecules.This interaction allows KIRs to identify virally infected cells or tumor cells by the distinctive low level of Class I MHC on their surface.The majority of KIRs are inhibitory，their recognition of MHC suppresses the cytotoxic activity of their NK cell.Only a limited number of KIRs have the capacity to activate cells.KIR2DL3 is an inhibitory Killer Cell Ig-like Receptor.KIR2DL3 recognizes class I MHC molecules (HLA-Cw1，-Cw3，-Cw7，and Cw8).KIR2DL3 inhibits the activity of NK cells thus preventing cell lysis.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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