Recombinant Human Mesothelin/MPF/MSLN/CAK1/Mes,BR

产品属性 Product Attributes

基本信息

别名： Megakaryocyte potentiating factor;mesothelin;Pre-pro-megakaryocyte-potentiating factor;soluble MPF mesothelin related protein;CAK1;MPF;MSLN;SMR;CAK1;CAK1 antigen
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Mesothelin is a cell surface glycoprotein whose expression is limited to mesothelial cells of the serosa (pleura，pericardium，and peritoneum) and epithelial cells of the trachea，tonsils，fallopian tube，and kidneys.Mesothelin plays an important role in cell survival，proliferation，migration，invasion，tumor progression，and resistance to chemotherapy.The overexpression of mesothelin can activate NF-κB and signal transducer and activator of transcription 3 (Stat3)，inhibit apoptotic signaling and TNF-α-induced apoptosis，and accelerate the G1–S transition.Mesothelin is also found overexpressed in various cancers，including malignant mesothelioma，pancreatic or ovarian carcinoma，sarcomas and in some gastrointestinal or pulmonary carcinomas.As a result of its limited expression in normal tissues，mesothelin has been reported as an ideal tumor-associated marker for the development of targeted therapy.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

暂无数据

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。