Recombinant Human Fc epsilon RII/CD23,BR

产品属性 Product Attributes

基本信息

别名： Low affinity immunoglobulin epsilon Fc receptor;BLAST-2;C-type lectin domain family 4 member J;Fc-epsilon-RII;Immunoglobulin E-binding factor;Lymphocyte IgE receptor;CD23;FCER2;CD23A;CLEC4J;FCE2;IGEBF
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Low affinity immunoglobulin epsilon Fc receptor(CD23) is a secreted and single-pass type II membrane protein which is also exists as a soluble excreted form.There are two forms of CD23: CD23a and CD23b.CD23a is present on follicular B cells，whereas CD23b requires IL-4 to be expressed on T-cells，monocytes，Langerhans cells，eosinophils，and macrophages.Unlike many of the antibody receptors，CD23/FCER2 is a C-type lectin.It is found on mature B cells，activated macrophages，eosinophils，follicular dendritic cells，and platelets.In flow cytometry，CD23/FCER2 is helpful in the differentiation of chronic lymphocytic leukemia (CD23-positive) from mantle cell leukemia (CD23-negative).CD23/FCER2 can also be demonstrated in germinal centre B-cells using immunohistochemistry，but it is not present in the resting cells of the surrounding mantle zone.CD23/FCER2 has essential roles in the regulation of IgE production and in the differentiation of B-cells (it is a B-cell-specificantigen).
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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