Recombinant Human B7 Homolog 6/B7-H6/NCR3LG1,BR

产品属性 Product Attributes

基本信息

别名： Natural cytotoxicity triggering receptor 3 ligand 1;B7 homolog 6;B7-H6;NCR3LG1;B7H6
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Natural cytotoxicity triggering receptor 3 ligand 1(B7-H6) is a glycosylated member of the B7 family of immune costimulatory proteins.Mature human B7-H6 consists of a 238 amino acid (aa) extracellular domain (ECD) that contains one Ig-like V domain and one Ig-like C1 domain，a 21 aa transmembrane segment，and a 171 aa cytoplasmic domain that contains one ITIM，one SH2，and one SH3 motif.Both of the Ig-like domains carry N-linked glycosylation.The Ig-like V domain mediates 1:1 stoichiometric binding of B7-H6 to NKp30 expressed on NK cells.It does not show binding to NKp44，NKp46，or NKG2D.Ligation of NKp30 by B7-H6 induces NK cell activation and target cell cytolysis.B7-H6 is expressed on a wide range of hematopoietic，carcinoma，and melanoma tumor cells，which is consistent with the detection of NKp30 binding sites on many tumors.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

暂无数据

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。