Recombinant Human B7-H4/VTCN1/B7 Homolog 4,BR

产品属性 Product Attributes

基本信息

别名： B7S1;B7x;Vtcn1;B7h.5;B7-H4;B7H4T-cell costimulatory molecule B7x;B7S1VCTN1;B7XPRO1291;FLJ22418;Immune costimulatory protein B7-H4;Protein B7S1;T cell costimulatory molecule B7x;V-set domain containing T cell activation inhibitor 1;V-set domain-containing T-cell activation inhibitor 1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins.Mature human B7-H4 consists of a 235 amino acid (aa) extracellular domain (ECD) with two Ig-like V-type domains，a 21 aa transmembrane segment，and a 2 aa cytoplasmic tail.It is widely expressed，including in kidney，liver，lung，pancreas，placenta，prostate，spleen，testis and thymus.B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation，proliferation，cytokine production and development of cytotoxicity.When expressed on the cell surface of tumor macrophages，plays an important role，together with regulatory T-cells (Treg)，in the suppression of tumor-associated antigen-specific T-cell immunity.It also involved in promoting epithelial cell transformation.
来源： Human Cells

其它标识

溶剂: Dissolve the lyophilized protein in distilled water.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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