Recombinant Human NGAL/Lipocalin-2/LCN2/Neutrophil gelatinase-associated lipocalin/p25,BR

产品属性 Product Attributes

基本信息

别名： Neutrophil gelatinase-associated lipocalin;NGAL;25 kDa alpha-2-microglobulin-related subunit of MMP-9;Lipocalin-2;Oncogene 24p3;Siderocalin LCN2;p25;HNL;NGAL
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of PBS, 50% glycerol,pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
运输条件： The product is shipped on dry ice/polar packs.Upon receipt，store it immediately at the temperature listed below.

产品信息

背景说明： LCN2 is iron-trafficking protein involved in multiple processes such as apoptosis，innate immunity and renal development.LCN2 binds iron through association with 2，5-dihydroxybenzoic acid (2，5-DHBA)，a siderophore that shares structural similarities with bacterial enterobactin，and delivers or removes iron from the cell，depending on the context.LCN2 is involved in apoptosis due to interleukin-3 (IL3) deprivation: iron-loaded form increases intracellular iron concentration without promoting apoptosis，while iron-free form decreases intracellular iron levels，inducing expression of the proapoptotic protein BCL2L11/BIM，resulting in apoptosis.LCN2 is involved in innate immunity，possibly by sequestrating iron，leading to limit bacterial growth.
来源： Human Cells

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。