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- Recombinant Human OGG1/N-glycosylase/DNA lyase,BR
Recombinant Human OGG1/N-glycosylase/DNA lyase,BR
Recombinant Human OGG1/N-glycosylase/DNA lyase
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产品属性 Product Attributes
基本信息
别名: N-Glycosylase/DNA Lyase;8-Oxoguanine DNA Glycosylase;DNA-(Apurinic or Apyrimidinic Site) Lyase;AP Lyase;OGG1;MMH;MUTM;OGH1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状): Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 1mM DTT, 1mM EDTA, 50% Glycerol, pH 7.8.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
产品信息
背景说明: Human N-Glycosylase/DNA Lyase(OOG1) is a DNA repair enzyme,which belongs to the type-1 OGG1 family.OOG1 incises DNA at 8-oxoG residues,and excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damage DNA.It has a β-lyase activity that nicks DNA 3’ to the lesion.OOG1 together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells.The OGG1 gene mutations may be caused Renal cell carcinoma.
来源: E.coli
其它标识
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
产品介绍 Product Introduction
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注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。