Recombinant Human WDYHV1/Protein N-terminal glutamine amidohydrolase,BR

产品属性 Product Attributes

基本信息

别名： Protein N-terminal glutamine amidohydrolase;WDYHV1;Protein NH2-terminal glutamine deamidase;N-terminal Gln amidase;Nt(Q)-amidase;C8orf32;NTAQ1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of PBS,100mM GSH,1% TritonX-100,15% Glycerol,pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Human protein N-terminal glutamine amidohydrolase (WDYHV1) is an enzyme that in humans is encoded by the WDYHV1 gene，belongs to the NTAQ1 family.WDYHV1 mediates the side-chain deamidation of N-terminal glutamine residues to glutamate，which is an important step in N-end rule pathway of protein degradation.Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation，polyubiquitination and degradation as specified by the N-end rule.However，it does not act on substrates with internal or C-terminal glutamine andnon-glutamine residues in any position.With the exception of proline，all tested second-position residues on substrate peptides do not greatly influence the activity.In contrast，a proline at position 2，virtually abolishes deamidation of N-terminal glutamine.
来源： E.coli

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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