Recombinant Human HMGB1/High mobility group protein B1/HMG-1,BR

产品属性 Product Attributes

基本信息

别名： High Mobility Group Protein B1;High Mobility Group Protein 1;HMG-1;HMGB1;HMG1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 50mM HEPES-Na,p H 7.9，500mM NaCl，0.6mM DTT.
纯度: ≥90% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： High mobility group protein B1 is a member of the HMGB family consisting of three members，HMGB1，HMGB2 and HMGB3.It Contains 2 HMG box DNA-binding domains entitled box A and box B and It is a highly negative-charged C terminus.As a nuclear protein，HMGB1 stabilizes nucleosomes and allows bending of DNA that facilitates gene transcription which is essential for individual survival.Meanwhile，it is revealed that HMGB1 can also act as a cytokine extracellularlly and regulates monocyte，T cell，dendritic cell activities in inflammatory responses.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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