Recombinant Human GITR Ligand/TNFSF18,BR

产品属性 Product Attributes

基本信息

别名： Tumor necrosis factor ligand superfamily member 18;TNFSF18;Activation-inducible TNF-related ligand;Glucocorticoid-induced TNF-related ligand;AITRL;GITRL;TL6
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥90% as determined by reducing SDS-PAGE.
储存条件: Powder:＜-20℃ for long store;RT，3 weeks.Liquid:4-7℃，2-7 days;＜-20℃，3 months.

产品信息

背景说明： TNFSF18 is a single-pass type II membrane protein.It is expressed at high levels in the small intestine，ovary，testis，kidney and endothelial cells.TNFSF18 cytokine binds to TNFRSF18/AITR/GITR.It regulates T-cell responses，and functions as costimulator and lower the threshold for T-cell activation and T-cell proliferation.It is Important for interactions between activated T-lymphocytes and endothelial cells and Promotes leukocyte adhesion to endothelial cells.TNFSF18 mediates activation of NF-kappa-B.As Triggers increased phosphorylation of STAT1 and up-regulates expression of VCAM1 and ICAM1.It also regulates migration of monocytes from the splenic reservoir to sites of inflammation.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

暂无数据

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。