Recombinant Mouse IGF Binding Protein 6/IGFBP-6,BR

产品属性 Product Attributes

基本信息

别名： Insulin-like growth factor-binding protein 6;IBP-6;IGF-binding protein 6;IGFBP-6;Igfbp6;IBP6;IGF binding protein 6;insulin-like growth factor-binding protein 6
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS,pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Insulin-like growth factors (IGFs) comprise a family of endocrine，paracrine and autocrine polypeptides consisting of the ligands IGF1 and IGF2，two receptors (IGF1R，IGF2R)，at least 6 IGF-binding proteins (IGFBPs) and IGFBP proteases.Among the binding proteins，IGFBP6 is unique because of its N-terminal disulfide linkages and its marked binding preference for IGF2.It is a potent inhibitor of the interaction between IGF2 and its receptor IGF1R，thus preventing major functions of IGF2，such as induction of proliferation，differentiation，cell adhesion，or colony formation.In particular，IGFBP-6 inhibited the growth of neuroblastoma and rhabdomyosarcoma xenografts.GFBP-6 is expressed in many tissues，including lung，liver，gut and the central nervous system.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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注意事项 Considerations

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