Recombinant Human IL-15 Receptor α & IL-15 Fusion Protein/IL15RA&IL15,BR

产品属性 Product Attributes

基本信息

别名： IL15RA&IL15;Interleukin-15;IL-15;IL15;IL-15 receptor subunit alpha;IL-15RA;IL-15R-alpha;interleukin-15 receptor subunit alpha
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS,5% Trehalose,ph7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： IL15RA is a high-affinity receptor for interleukin-15.Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits to initiate signal transduction.It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells.Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells.IL-15 is a cytokine that regulates T cell and natural killer cell activation and proliferation.IL-15 binds to the alpha subunit of the IL-15RA with high affinity.IL-15 also binds to the beta and gamma chains of the IL-2 receptor，but not the alpha subunit of the IL2 receptor.IL-15 is structurally and functionally related to IL-2.Both cytokines share some subunits of receptors，allowing them to compete for and negatively regulate each other's activity.The number of CD8+ memory T cells is controlled by a balance between IL-15 and IL-2.Despite their many overlapping functional properties，IL-2 and IL-15 are，in fact，quite distinct players in the immune system.IL-15 is constitutively expressed by a wide variety of cell types and tissues，including monocytes，macrophages and DCs.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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