Recombinant Human EIF4EBP1,BR

产品属性 Product Attributes

基本信息

别名： Eukaryotic Translation Initiation Factor 4E-Binding Protein 1;4E-BP1;eIF4E-Binding Protein 1;Phosphorylated Heat- and Acid-Stable Protein Regulated by Insulin 1;PHAS-I;EIF4EBP1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) is a number of the eIF4E-binding protein family.4EBP1 regulates eIF4E activity by preventing its assembly into the eIF4F complex.4EBP1 mediates the regulation of protein translation by hormones，growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.Non-phosphorylated 4EBP1 competes with EIF4G1/EIF4G3 to interact with EIF4E.4EBP1 is phosphorylated in response to various signals including insulin signaling，resulting in its dissociation from eIF4E and activation of mRNA translation.4EBP1 has a role in progression of breast neoplasms through cell signaling.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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