Recombinant Mouse TREM-1/CD354/Triggering receptor expressed on myeloid Cells 1,BR

产品属性 Product Attributes

基本信息

别名： Triggering receptor expressed on myeloid cells 1;TREM-1;CD354;Trem1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1) is a transmembrane protein with a single Ig-like domain.TREM-1 associates with the adapter protein，DAP12，to deliver an activating signal.TREM-1 is expressed on blood neutrophils and monocytes，and the expression is up-regulated by bacterial LPS.TREM-1 is expressed at high levels on neutrophils of patients with microbial sepsis and in mice with a TREM-1/Fc fusion protein protected mice against LPS-induced shock.It stimulates neutrophil and monocyte-mediated inflammatory responses.Triggers release of pro-inflammatory chemokines and cytokines，as well as increased surface expression of cell activation markers.TREM-1 is amplifier of inflammatory responses that are triggered by bacterial and fungal infections and are a crucial mediator of septic shock.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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