Recombinant Human IL-4 R alpha/CD124/IL-4RA/IL-4R/Interleukin-4 Receptor Subunit Alpha/prot,BR

产品属性 Product Attributes

基本信息

别名： Interleukin-4 receptor subunit alpha;IL-4 receptor subunit alpha;IL-4R subunit alpha;IL-4R-alpha;IL-4RA;CD124;IL-4-binding protein;IL4-BP;IL4R;IL4RA
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS,pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Interleukin 4 Receptor alpha (IL4-Ra) is a widely expressed 140 kDa transmembrane glycoprotein in the class I cytokine receptor family.Mature human IL4-Ra consists of a 207 amino acid (aa) extracellular domain (ECD) that contains a cytokine binding region and one fibronectin type III domain，a 24 aa transmembrane segment，and a 569 aa cytoplasmic domain that contains one Box 1 motif and one ITIM motif.IL4-Ra plays an important role in Th2-biased immune responses，alternative macrophage activation，mucosal immunity，allergic inflammation，tumor progression，and atherogenesis.Soluble forms of IL4-Ra，generated by alternate splicing or proteolysis，retain ligand binding properties and inhibit IL-4 bioactivity.
来源： Human Cells

其它标识

溶剂: Dissolve the lyophilized protein in distilled water.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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