Recombinant Human Brain-specific angiogenesis inhibitor 3/BAI3,BR

产品属性 Product Attributes

基本信息

别名： Brain-Specific Angiogenesis Inhibitor 3;BAI3;KIAA0550
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 5% Thehalose, pH 7.2.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Human Brain-Specific Angiogenesis Inhibitor 3 (BAI3) is a 177 kDa seven-span transmembrane (TM) protein，which is thought to be a member of the secretin receptor family.It is synthesized by neurons of the CNS and likely is a negative regulator of angiogenesis.BAI3 is 1498 amino acids in size.It contains three distinct regions: an N-terminal extracellular domain (ECD) (aa25-883)，a 7-TM segment，and a C-terminal cytoplasmic region.The ECD contains four antiangiogenic TSP type 1 repeat (aa296-508)，and one GSP domain (aa 816-867) that is likely used to cleave the ECD from the membrane-bound receptor.There is one altermate splice form that shows a deletion of aa 643-665.Over aa 25-880，human BAI3 shares 98% aa identity with mouse BAI3.BAI3 has been reported primarily in the brain，but is also localized to lung，testis，and pancreas.It might be involved in angiogenesis inhibition and suppression of glioblastoma.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/μg(1 EU/μg)as determined by LAL test.

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