Recombinant Human Serpin G1,BR

产品属性 Product Attributes

基本信息

别名： Plasma Protease C1 Inhibitor;C1 Inh;C1Inh;C1 Esterase Inhibitor;C1-Inhibiting Factor;Serpin G1;SERPING1;C1IN;C1NH
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： As protease inhibitors，serpins have an array of functions including regulating blood clotting，the complement pathway，extracellular matrix remodeling，and cell motility.Serpin G1 is a serine protease inhibitor protein.It is the largest member among the serpin class of proteins.Remarkably，Serpin G1 has a 2-domain structure，unlike most family members.The C-terminal serpin domain is similar to other serpins，and this part of Serpin G1 provides the inhibitory activity.The N-terminal domain is not essential for Serpin G1 to inhibit proteinases and has no similarity to other proteins.The main function of Serpin G1 is the inhibition of the complement system to prevent spontaneous activation.Serpin G1 is an acute phase protein and circulates in blood at levels of around 0.25g/L，whose levels rise 2-fold during inflammation.Although named after its complement inhibitory activity，Serpin G1 also inhibits proteinases of the fibrinolytic，clotting，and kinin pathways.Most notably，Serpin G1 play a potentially crucial role in regulating important physiological pathways including complement activation，blood coagulation，fibrinolysis and the generation of kinins.It is also the most important physiological inhibitor of fXIIa，chymotrypsin and plasma kallikrein.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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