Recombinant Human Prolactin/PRL,BR

产品属性 Product Attributes

基本信息

别名： Prolactin;PRL;
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM Nacl, 1mM EDTA, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Prolactin (PRL) is a secreted neuroendocrine pituitary hormone that acts primarily on the mammary gland to promote lactation，but has pleiotropic effects in both males and females.Non-glycosylated prolactin is produced by the pituitary and packaged in storage granules before secretion，while glycosylated prolactin is reported to be constitutively secreted，have lower biological potency，and be removed from the circulation more quickly.Prolactin is synthesized mainly by the anterior pituitary in all mammals，where secretion is under tonic inhibition by hypothalamic dopamine.In humans，prolactin is also produced peripherally.Prolactin expression is low during early human pregnancy，but increases in late pregnancy.The prolactin receptor (PRLR) is a transmembrane type I glycoprotein that belongs to the cytokine hematopoietic receptor family.prolactin molecule is thought to bind two receptor molecules.In addition to its lactogenic activity，peripherally produced prolactin plays roles in breast and prostate cancer development，regulation of reproductive function，and immunoregulation.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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