Recombinant Human LDLR/Low-density lipoprotein receptor,BR

产品属性 Product Attributes

基本信息

别名： Low-Density Lipoprotein Receptor;LDL Receptor;LDLR
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM HEPES,150mM Nacl,PH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Low-Density Lipoprotein Receptor (LDLR) is a transmembrane glycoprotein that plays a critical role in cholesterol homeostasis.LDLR mediates blood cholesterol level by interacting with lipoprotein particles like LDL and VLDL.The extracellular domain of LDLR contains LDL receptor type A (ligand-binding) modules (LA repeats)，epidermal growth factor-like modules，and LY repeats containing the YWTD consensus motif that are important in binding and releasing of ApoB-100 and ApoE in lipoprotein particles.The C terminal domain of LDLR inside the cell is required for the receptor internalization.Loss of function mutations in the LDLR gene causes Familial Hypercholesterolemia (FH).
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。