Recombinant Mouse IL-17/IL-17A,BR

产品属性 Product Attributes

基本信息

别名： Interleukin-17A;IL-17;IL-17A;Cytotoxic T-Lymphocyte-Associated Antigen 8;CTLA-8;IL17A;CTLA8;IL17
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS,PH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells.There are at least six members of the IL-17 family in humans and in mice.Mature mouse IL-17A shares 61% and 89% amino acid sequence identity with human and rat IL-17A，respectively.As IL-17 shares properties with IL-1 and TNF-alpha，it may induce joint inflammation and bone and cartilage destruction.This cytokine is found in synovial fluids of patients with rheumatoid arthritis，and produced by rheumatoid arthritis synovium.It increases IL-6 production，induces collagen degradation and decreases collagen synthesis by synovium and cartilage and proteoglycan synthesis in cartilage.IL-17 is also able to increase bone destruction and reduce its formation.Blocking of interleukin-17 with specific inhibitors provides a protective inhibition of cartilage and bone degradation.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。