Recombinant Human IL-36RA/IL-36RN/IL-1F5/IL-36 Receptor Antagonist Protein,BR

产品属性 Product Attributes

基本信息

别名： IL-36RA;IL-36Ra;Interleukin-36 Receptor Antagonist Protein;FIL1 Delta;IL-1-Related Protein 3;IL-1RP3;Interleukin-1 HY1;IL-1HY1;Interleukin-1 Delta;IL-1 Delta;Interleukin-1 Family Member 5;IL-1F5;Interleukin-1 Receptor Antagonist Homolog 1;IL-1ra Homolog 1;Interleukin-1-Like Protein 1;IL-1L1;IL36RN;FIL1D;IL1F5;IL1HY1;IL1L1;IL1RP3
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Human Interleukin-36 Receptor Antagonist (IL-36RN) is a secreted protein which belongs to the Interleukin 1 cytokine family (IL-1 family).IL-36RN is predominantly expressed in keratinocytes but not in fibroblasts，endothelial cells or melanocytes.IL-36RN is also detected in the spleen，brain leukocyte and macrophage cell types.Increased in lesional psoriasis skin.IL-36RN is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to Interleukin 1 family member 9 (IL1F9).Dysregulated expression of novel agonistic and antagonistic IL-1 family member ligands can promote cutaneous inflammation，revealing potential novel targets for the treatment of inflammatory skin disorders.Human and mouse IL-36RN share 90% sequence identity.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

暂无数据

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。