Recombinant Human Serpin A7/TBG,BR

产品属性 Product Attributes

基本信息

别名： Thyroxine-Binding Globulin;Serpin A7;T4-Binding Globulin;SERPINA7;TBG
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Serpin A7 is a secreted protein which belongs to the Serpin family.As a 54 kDa protein，Serpin A7 is synthesized primarily in the liver and secreted in plasma.Genomically，Serpin A7 is a serpin，although it has no inhibitory function like many other members of this class of proteins.Serpin A7 binds thyroid hormone in circulation.It is one of three proteins (along with transthyretin and albumin) responsible for carrying the thyroid hormones thyroxine (T4) and 3，5，3’-triiodothyronine (T3) in the bloodstream.Of these three proteins，Serpin A7 has the highest affinity for T4 and T3，but is present in the lowest concentration.Despite its low concentration，Serpin A7 carries the majority of T4 in serum.Due to the very low serum concentration of T4 and T3 in the blood，Serpin A7 is rarely more than 25% saturated with its ligand.Unlike transthyretin and albumin，Serpin A7 has a single binding site for T4/T3.Serpin A7 tests are sometimes used in finding the reason for elevated or diminished levels of thyroid hormone，and defects in Serpin A7 are a cause of Serpin A7 deficiency.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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