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- Recombinant Human CCL26/Eotaxin-3 (27-94),BR
Recombinant Human CCL26/Eotaxin-3 (27-94),BR
Recombinant Human CCL26/Eotaxin-3 (27-94)
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产品属性 Product Attributes
基本信息
别名: C-C Motif Chemokine 26;CC Chemokine IMAC;Eotaxin-3;Macrophage Inflammatory Protein 4-Alpha;MIP-4-Alpha;Small-Inducible Cytokine A26;Thymic Stroma Chemokine-1;TSC-1;CCL26;SCYA26规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状): Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
产品信息
背景说明: Chemokine (C C Motif) Ligand 26 (CCL26) is a novel small cytokine belonging to the CC chemokine family,which involved in immunoregulatory and inflammatory processes.CCL26 is expressed constitutively in thymus,but only transiently in phytohemagglutinin-stimulated peripheral blood mononuclear cells.It specifically binds and induces chemotaxis in T cells and elicits its effects by interacting with the chemokine receptor CCR4.Eotaxin-3/CCL26,along with Eotaxin-1 and Eotaxin-2,selectively activates the CC chemokine receptor 3 (CCR3).The Eotaxin-3-CCR3 interaction may play an important role in allergic diseases such as atopic dermatitis and bronchial asthma.The full-length cDNA for Eotaxin-3 encodes a protein of 94 amino acids with a putative signal peptide of either 23 or 26 amino acid residues.Both the 71 and 68 amino acid residue variants of recombinant Eotaxin-3 demonstrate equal potency in inducing chemotaxis of a human CCR3-transfected cell line.Unlike most other CC chemokines,Eotaxin-3 maps to human chromosome 7q11.2,within 40 kilobases of the Eotaxin-2 loci.Eotaxin-3 and Eotaxin-2 are unique in that they are the only chemokines identified to date that map to chromosome 7.来源: E.coli
其它标识
溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.
产品介绍 Product Introduction
暂无数据注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。