Recombinant Human PHS/PCBD1,BR

产品属性 Product Attributes

基本信息

别名： Pterin-4-Alpha-Carbinolamine Dehydratase;PHS;4-Alpha-Hydroxy-Tetrahydropterin Dehydratase;Dimerization Cofactor of Hepatocyte Nuclear Factor 1-Alpha;DCoH;Dimerization Cofactor of HNF1;Phenylalanine Hydroxylase-Stimulating Protein;Pterin Carbinolamine Dehydratase;PCD;PCBD1;DCOH;PCBD
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 1mM DTT, pH 8.0.
纯度: ≥90% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Pterin-4-α-Carbinolamine Dehydratase (PCBD1) is the founding member of the Pterin-4-α-Carbinolamine Dehydratase Family.PCBD1 is involved in Tetrahydrobiopterin biosynthesis.It seems to prevent the formation of 7-Pterins and accelerate the formation of Quinonoid-BH2.Furthermore，PCBD1 regulates the homodimerization of the transcription factor Hepatocyte Nuclear Factor 1 (HNF1) and enhances its transcriptional activity.Defects in PCBD1 are the cause of BH4-Deficient Hyperphenylalaninemia Type D (HPABH4D).HPABH4D is characterized by the excretion of 7-substituted Pterins in the urine of affected patients.
来源： E.coli

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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