Recombinant Human PTPRN（578-859）,BR

产品属性 Product Attributes

基本信息

别名： Receptor-type tyrosine-protein phosphatase-like N;R-PTP-N;Islet cell antigen 512;ICA 512;Islet cell autoantigen 3;PTP IA-2;PTPRN;ICA3;ICA512
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： Receptor-type tyrosine-protein phosphatase-like N (PTPRN) belongs to the protein-tyrosine phosphatase family and receptor class 8 subfamily.PTPRN contains 1 tyrosine-protein phosphatase domain，is expressed in neuroendocrine cells only.PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth，differentiation，mitotic cycle，and oncogenic transformation.It implicated in neuroendocrine secretory processes.It may be involved in processes specific for neurosecretory granules，such as their biogenesis，trafficking or regulated exocytosis or may have a general role in neuroendocrine functions.It seems to lack intrinsic enzyme activity，may play a role in the regulation of secretory granules via its interaction with SNTB2.This PTP was found to be an autoantigen that is reactive with insulin-dependent diabetes mellitus (IDDM) patient sera，and thus may be a potential target of autoimmunity in diabetes mellitus.
来源： E.coli

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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