Recombinant Human BUP-1/UPB1/β-ureidopropionase,BR

产品属性 Product Attributes

基本信息

别名： Beta-Ureidopropionase;BUP-1;Beta-Alanine Synthase;N-Carbamoyl-Beta-Alanine Amidohydrolase;UPB1;BUP1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： β-Ureidopropionase is a cytoplasmic protein which belongs to the CN hydrolase family of BUP subfamily.β-Ureidopropionase binds one zinc ion per subunit，catalyzes the last step in the pyrimidine degradation pathway.β-Ureidopropionase can convert N-carbamyl-beta-aminoisobutyric acid and N-carbamyl-beta-alanine to beta-aminoisobutyric acid and beta-alanine，ammonia and carbon dioxide，respectively.The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH)，dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta aminoisobutyric acid，respectively.Defects in β-Ureidopropionase are the cause of β-Ureidopropionase deficiency that is characterized by muscular hypotonia，dystonic movements，scoliosis，microcephaly and severe developmental delay.
来源： E.coli

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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