Recombinant Human Bcl-2-like Protein 11/BIML,BR

产品属性 Product Attributes

基本信息

别名： Bcl-2-like protein 11;Bcl2-L-11;Bcl2-interacting mediator of cell death;BCL2L11;BIM;BIML
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM HEPES, 150mM NaCl, 10% glycerol, 2mM DTT, pH8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at≤-70℃，6 months.with seal;3 month after opening.Avoid freeze/thaw cycles.

产品信息

背景说明： BIML is one of several splice variants of BIM，a proapoptotic protein belonging to the BH-3 domain-only subgroup of Bcl-2 family members.BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities.BIML is thought to promote apoptosis by binding and inhibiting the activity of anti-apoptotic Bcl-2 family members，thereby inducing the release of cytochrome c from mitochondria.BIML is normally sequestered in an inactive conformation from anti-apoptotic Bcl-2 family members through binding to the microtubule-associated dynein motor complex.Certain apoptotic stimuli release BIML from microtubules to neutralize anti-apoptotic Bcl-2 family members，allowing for the initiation of apoptosis.
来源： E.coli

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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