Recombinant Human PGDH(15-PGDH)/HPGD,BR

产品属性 Product Attributes

基本信息

别名： 15-Hydroxyprostaglandin Dehydrogenase [NAD(+)];15-PGDH;Prostaglandin Dehydrogenase 1;HPGD;PGDH1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM HEPES,150mM NaCl,pH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

产品信息

背景说明： 15-hydroxyprostaglandin dehydrogenase [NAD(+)]，also known as Prostaglandin dehydrogenase 1，15-PGDH，HPGD and PGDH1，belongs to the short-chain dehydrogenases/reductases (SDR) family.HPGD localizes to the cytoplasm and can be found in colon epithelium，existing as a homodimer.HPGD catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4.HPGD is down-regulated by cortisol，dexamethasone and betamethasone，up-regulated by TGFB1.HPGD inhibits in vivo proliferation of colon cancer cells.HPGD is the key enzyme for the inactivation of prostaglandins，and thus regulates processes such as inflammation or proliferation.
来源： Human Cells

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。