Recombinant Human PAPSS1,BR

产品属性 Product Attributes

基本信息

别名： Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1;PAPS synthase 1;PAPSS 1;Sulfurylase kinase 1;SK 1;ATPSK1;PAPSS
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Supplied as a 0.2 μm filtered solution of 20mM Tris,100mM NaCl,20% glycerol,pH 8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at≤-70℃，6 months.with seal;3 month after opening.Avoid freeze/thaw cycles.

产品信息

背景说明： PAPSS1 is a bifunctional enzyme with both ATP sulfurylase and APS kinase activity.In the N-terminal section，it belongs to the APS kinase family; while the C-terminal section belongs to the sulfate adenylyltransferase family.PAPSS1 can be inhibited by chlorate，and is expressed in many tissues，such as high endothelial venules (HEV) cells and in cartilage.PAPSS1 mediates two steps in the sulfate activation pathway.The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS)，and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate.In mammals，PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate-activation pathway.PAPSS1 also involved in the biosynthesis of sulfated L-selectin ligands in endothelial cells.
来源： Human Cells

其它标识

内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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