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- Recombinant Human MMP-1/Interstitial collagenase,BR
Recombinant Human MMP-1/Interstitial collagenase,BR
Recombinant Human MMP-1/Interstitial collagenase
(订货以英文名为准)猜你喜欢
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产品属性 Product Attributes
基本信息
别名: Interstitial Collagenase;Fibroblast Collagenase;Matrix Metalloproteinase-1;MMP-1;MMP1;CLG规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状): Supplied as a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, 0.05% Brij35, 10% Glycerol, pH 5.5.Note: The proenzyme needs to be activated by APMA.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.
产品信息
背景说明: Matrix Metalloproteinase-1 (MMP-1) is expressed by fibroblasts,keratinocytes,endothelial cells,monocytes and macrophages.MMP1 contains several distinct domains: a prodomain that is cleaved upon activation,a catalytic domain containing the zinc binding site,a short hinge region,and a carboxyl terminal (hemopexin like) domain.MMP-1 can degrade a broad range of substrates including types I,II,III,VII,VIII,and X collagens as well as casein,gelatin,α1 antitrypsin,myelin basic protein,L-Selectin,pro-TNF,IL1,IGFBP3,IGFBP5,pro-MMP2,and pro-MMP9.A significant role of MMP1 is the degradation of fibrillar collagens in extracellular matrix remodeling,characterized by the cleavage of the interstitial collagen triple helix into 3/4,1/4 fragments.MMP1 may also be involved in enzyme cascades,cytokine regulation and cell surface molecule modulation.来源: Human Cells
其它标识
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.产品介绍 Product Introduction
暂无数据注意事项 Considerations
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响,相关处理只限于产品本身,不涉及其他赔偿。