Recombinant Human ATP-binding cassette sub-family B member 5/ABCB5,BR

产品属性 Product Attributes

基本信息

别名： ATP-binding cassette sub-family B member 5;P-glycoprotein ABCB5;ABCB5 P-gp;ABCB5;
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM PB，150mM NaCl,pH7.4.
纯度: ≥90% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： ATP-binding cassette sub-family B member 5(ABCB5) is a plasma membrane-spanning protein.ABCB5 is principally expressed in physiological skin and human malignant melanoma.ABCB5 has been suggested to regulate skin progenitor cell fusion and mediate chemotherapeutic drug resistance in stem-like tumor cell subpopulations in human malignant melanoma.It is commonly over-expressed on circulating melanoma tumour cells.Furthermore，the ABCB5+ melanoma- initiating cells were demonstrated to express FLT1 (VEGFR1) receptor tyrosine kinase which was functionally required for efficient xenograft tumor formation，as demonstrated by shRNA knockdown experiments.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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