Recombinant Mouse IL-13(Ser26-Phe131),BR

产品属性 Product Attributes

基本信息

别名： Interleukin-13;IL-13;T-Cell Activation Protein P600;Il13;Il-13
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥90% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Mouse interleukin 13 (mIL-13) is a pleiotropic cytokine produced by activated Th2 cells.IL-13 induces B cell proliferation and immunoglobin production.It contains a four helical bundle with two internal disulfide bonds.Mouse IL13 shares 58% sequence identity with human protein and exhibits cross-species activity.IL13 signals via receptor IL13R (type2，IL4R) and activates STAT-6.IL13 initially binds IL-13Rα1 with low affinity and triggers association of IL4Rα，generating a high affinity heterodimeric receptor IL13R and eliciting downstream signals.IL13 also binds IL-13Rα2 with high affinity，which plays a role in a negative feedback system of IL13 signaling.IL13 is an important mediator of allergic inflammation and disease.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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