Recombinant Human Ganglioside GM2 activator/GM2A,BR

产品属性 Product Attributes

基本信息

别名： Ganglioside GM2 activator;Cerebroside sulfate activator protein;GM2-AP;Sphingolipid activator protein 3;SAP-3
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl,150mM NaCl,pH7.5.
纯度: ≥90% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Ganglioside GM2 activator (GM2A) is a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme β-hexosaminidase A (HEXB).HEXB together with GM2A，catalyzes the degradation of the ganglioside GM2，and other molecules containing terminal N-acetyl hexosamines.GM2A accommodate several single chain phospholipids and fatty acids，is a lipid transfer protein that stimulates the enzymatic processing of gangliosides，and also T-cell activation through lipid presentation.It extracts single GM2 molecules from membranes and presents them in soluble form to beta-hexosaminidase A for cleavage of N-acetyl-D-galactosamine and conversion to GM3.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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