Recombinant Mouse Serpin G1/Serping1/C1nh,BR

产品属性 Product Attributes

基本信息

别名： SERPIN G1;Plasma protease C1 inhibitor;C1 Inh;C1 esterase inhibitor;C1-inhibiting factor;Serping1;C1nh
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl,pH8.0.
纯度: ≥90% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： SERPIN G1 is a member of the serpin family，The C-terminal serpin domain is similar to other serpins，and this part of C1-INH provides the inhibitory activity.SERPIN G1 is involved in the inhibition of the complement system to prevent spontaneous activation.SERPIN G1 may play a potentially crucial role in regulating important physiological pathways including complement activation，blood coagulation，fibrinolysis and the generation of kinins.SERPIN G1 prevents the proteolytic cleavage of later complement components C4 and C2 by C1 and MBL.SERPIN G1 is a very efficient physiological inhibitor of FXIIa，plasma kallikrein and fXIa，and could inhibit chymotrypsin and kallikrein.It forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases in the C1 complex of classical pathway of complement.Activation of the C1 complex is under control of the C1-inhibitor.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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注意事项 Considerations

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