Recombinant Human Tryptase alpha/beta-1/TPSAB1,BR

产品属性 Product Attributes

基本信息

别名： tryptase alpha/beta 1;Tryptase 1;TPS1;TPS2;TPSAB1;TPSB1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 1M NaCl, 0.05mM Heparin, 50mM sodium acetate, pH5.0, containing 0.01% sodium azide.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Tryptases are serine proteases with trypsin-like specificity.Together with chymases and Cathepsin G，tryptases are important players in mast cell mediation of inflammatory and allergic responses.Tryptase alpha/beta-1(TPSAB1)，also known as mast cell protease 7 (MCPT7)，it exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of a diverse array of protease inhibitors in plasma.The two Isoform 1 and isoform 2 are expressed in lung，stomach，spleen，heart and skin; in these tissues，isoform 1 is predominant.Isoform 2 is expressed in aorta，spleen，and breast tumor，with highest levels in the endothelial cells of some blood vessels surrounding the aorta，as well as those surrounding the tumor and low levels，if any，in mast cells.Isoform 2 cleaves large substrates，such as fibronectin，more efficiently than isoform 1，but seems less efficient toward small substrates.It may play a role in innate immunity.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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