Recombinant Human Olfactomedin-4/OLFM4,BR

产品属性 Product Attributes

基本信息

别名： Olfactomedin-4;OLM4;Antiapoptotic protein GW112;G-CSF-stimulated clone 1 protein;hGC-1;hOLfD;OLFM4;GW112
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS,5%Trehalose,PH7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Olfactomedin-4/OLFM4 is a secreted protein which contains one olfactomedin-like domain.OLFM4 is expressed during myeloid lineage development，it strongly expressed in the prostate，small intestine，colon and moderately expressed in the bone marrow and stomach.OLFM4 is an antiapoptotic factor that promotes tumor growth.It expressed at high levels in stomach cancer and colon cancer tissues.it promotes proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase.In myeloid leukemic cell lines，OLFM4 inhibits cell growth and induces cell differentiation and apoptosis.Through interaction with cell surface lectins and cadherin，OLFM4 facilitates cell adhesion.It may play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation.Induction of OLFM4 in cancer cells was reported to have a novel antiapoptotic action via binding to the potent apoptosis inducer GRIM-19.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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