Recombinant Cynomolgus Siglec-5/CD170/CD33L2/CD33 antigen-like 2/Obesity-binding protein 2/OBBP2,BR

产品属性 Product Attributes

基本信息

别名： Sialic acid-binding Ig-like lectin 5;Siglec-5
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH8.0.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Sialic acid-binding Ig-like lectin 5 is a protein that in Cynomolgus is encoded by the SIGLEC5 gene，Cynomolgus SIGLEC5 cDNA encodes 551 amino acids (aa) that include a 16 aa signal sequence，a439aa extracellular domain (ECD) with three Ig-like domains，a transmembrane region and a cytoplasma tail.No Siglec has been shown to recognized any cell surface ligand other than sialic acids，suggesting that interactions with glycans containing this carbohydrate are important in mediating the biological functions of Siglecs.Siglec5 to 11 share a high degree of sequence similarity with CD33/Siglec3 both in their extracellular and intracellular regions.Putative adhesion molecule that mediates sialic-acid dependent binding to cells.Binds equally to alpha-2，3-linked and alpha-2，6-linked sialic acid.The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
来源： Human Cells

其它标识

溶剂: Dissolve the lyophilized protein in distilled water.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

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