Recombinant Human Z-DNA-binding protein 1/ZBP1,BR

产品属性 Product Attributes

基本信息

别名： Z-DNA-Binding Protein 1;Tumor Stroma and Activated Macrophage Protein DLM;ZBP1;C20orf183;DLM1
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Z-DNA Binding Protein 1 (ZBP1) is a protein with 2 DRADA repeats.ZBP1 is highly expressed in lymphatic tissues including lymph node，leukocytes，tonsil，bone marrow，and spleen.ZBP1 participates in the detection of viral and bacterial DNA from by the host's innate immune system.It plays a role in host defense against tumors and pathogens.ZBP1 Acts as a cytoplasmic DNA sensor which，when activated，induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor (IRF) and NF-kappa B transcription factors，leading to type-I interferon production.ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3.
来源： E.coli

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

产品介绍 Product Introduction

暂无数据

注意事项 Considerations

1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
3.实验结果可由多种因素影响，相关处理只限于产品本身，不涉及其他赔偿。