Recombinant Human Serpin A5/Protein C Inhibitor,BR

产品属性 Product Attributes

基本信息

别名： Plasma Serine Protease Inhibitor;Acrosomal Serine Protease Inhibitor;Plasminogen Activator Inhibitor 3;PAI-3;PAI3;Protein C Inhibitor;PCI;Serpin A5;SERPINA5;PCI;PLANH3;PROCI
规格: 10ug ; 50ug ; 500ug ; 1mg
外观(性状)： Lyophilized from a 0.2 μm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.
纯度: ≥95% as determined by reducing SDS-PAGE.
储存条件: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

产品信息

背景说明： Serpin A5 is a member of the human Serpin superfamily consists of at least 35 members.It is synthesized in the liver and has been detected in saliva，cerebral spinal fluid，amniotic fluid，tears and semen.As a potent inhibitor of the protein C anticoagulant pathway at the levels of both zymogen activation and enzyme inhibition，Serpin A5 additionally inhibits a variety of serine protease including thrombin，factor Xa，several kallekreins and acrosin.It plays a critical role in the processes of blood of blood coagulation and fertilization.Serpin A5 also inhibits urinary plasminogen activator (uPA)，a mediator of tumor cell invasion，and regulates tumor growth and metastasis by inhibiting angiogenesis.Furthermore，recent studies have identified PCI as a potent and direct inhibitor of activated HGFA (hepatocyte growth factor activator)，suggesting a novel function in the regulation of tissue repair and regeneration.Similar to Serpins C1 and D1，the thrombin inhibitory activity of serpinA5 is enhanced by heparin.
来源： Human Cells

其它标识

溶剂: Always centrifuge tubes before opening.Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
内毒素: Less than 0.1 ng/ug(1 EU/ug)as determined by LAL test.

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